Biological responses of the rat to polychlorinated biphenyls
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چکیده
منابع مشابه
Biological responses of the rat to polychlorinated biphenyls.
Biological Responses of the Rat to Polychlorinated Biphenyls. BRUCKNER, J. V., KHANNA, K. L. and CORNISH, H. H. (1973). Toxicol. Appl. Pharmacol. 24, 434-448. A commercial polychlorinated biphenyl mixture (PCBs), Aroclor 1242, was administered to rats po by intubation in order to determine toxic manifestations of acute and subacute ingestion. In addition, the effect of PCBs on hepatic microsoma...
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A b s t r a e ~ A r o c l o r 1242, a commercial polychlorinated biphenyl mixture, was fed to rats at dietary levels of 0, 5 and 25 ppm for 2, 4 and 6 months. Significant elevations of urinary coproporphyrin excretion, hepatic lipid and hepatic microsomal-hydroxylase activity were observed in rats ingesting 25 ppm for 2 months. In rats given the 5 or 25 ppm regimens for 4 or 6 months, urinary c...
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Polychlorinated biphenyls (PCBs) are industrial compounds with multiple industrial and commercial uses (Table 41.1). PCBs are chemically inert and stable when heated. These properties contribute greatly to PCBs having become environmental contaminants. The chemical inertness and heat stability properties that make PCBs desirable for industry also protect them from destruction when the products ...
متن کاملFood Exposures to Polychlorinated Biphenyls
The PCB family of industrial chemicals has been used in a number of useful and beneficial ways for more than 40 years. PCBs have been used in capacitors, as transformer fluids, as heat transfer agents, in plasticizers and adhesives, and in sealants and printing inks. Needless to say, they have no place in the nation's food supply. The scientific community has been aware of the potential hazard ...
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ژورنال
عنوان ژورنال: Toxicology and Applied Pharmacology
سال: 1973
ISSN: 0041-008X
DOI: 10.1016/0041-008x(73)90050-1